Hi Joel,
1) You can crop before denoising. The flatfield must be cropped likewise. With DynamicCrop, set the crop bounds on the image, but before committing, drag the process icon to the flatfield, then commit on the image. Both should be cropped the same way.
2) Select and copy all of the lines in the Process Console window generated by ImageIntegration, use the Script Editor window to paste the lines into a new .txt file, save, and then load in the script. The denoiser will set Variance scale to account for the average frame normalization and weighting.
Thanks,
Mike