I took 30 4 min subs that were c,d,r and tried to run with 10 minute subsx4.
I don't understand this sentence. What do "c,d,r" and "subsx4" mean?
In any case, you have to calibrate, register and integrate separately the 4 minute and 10 minute images. The registration must be done using the same reference image. If there are strong gradients you should remove them before HDRComposition.