After much chasing of virus scanner settings, firewall settings, possible left overs from old security software suites that have been uninstalled and replaced with new. Chasing of Windows settings, posting on windows user forums for some input, none of which did anything to resolve the PixInsight error as listed above, I found a solution. I once again did an uninstall with the PixInsight uninstaller, restarted the machine(s), opened PixInsight and attempted to update once again... Same error, so I used the PixInsight "Reset PixInsight Settings", and Restarted again.
Guess What!!! This solved the update problem on all three of my systems... The Observatory Desktop, my main work Station desktop in the house and my notebook I use for travel. The only system I had done the problem chasing on which proved out to make no difference was the main work station desktop... the other two have not been monkeyed with at all. Figured I would not be beating about within their files, security applications and such untile I had found the possible culprit within the Windows and/or Security Suite application(s) The work station is a Windows 7 Pro, the other two are Windows 10 pro (upgrade from 7 Pro)... Same solution worked on all three systems, leads me to believe the problem was something within the settings somewhere within the PixInsight application. Possibly something had caused the same file corruption on all three systems!!???... Hard to believe that as the Observatory desktop is only used for observatory related workings & such.
Anyhow the "Reset PixInsight Settings" has resolved the issue on all three systems.... !!! Yaaayyyyy, I can install the updates once again!