Dave,
A quick edit here. I have no idea why I read 3 subs per filter from!!. But having said that I hope the other tips are of some use to you.As you only used
three subs from each filter, your not going to get a good result. I have found that although three is the minimum number of subs you can integrate in PI there is no or very little rejection taking place. There is a slight improvement with 4 subs, but do 5 and there is suddenly a big improvement. So I suggest using 5 subs as a minimum (but more the better). If time on the telescope is restricted, then I suspect you may get a better result taking more subs of a shorter exposure time. So for example instead of taking 3 x 5min subs, take 5 x 3min subs.
Most of the bright colours in your image are probably from hot/warm pixels that are not being rejected due to the small number of subs.
I also think that you may have applied too much colour saturation which is exaggerating the problem.
You can always take extra subs of the same object on another night and then integrate them altogether, so your data/time has not been wasted.
You can also make a pixel rejection map from the telescopes dark frames, then use defect map that will remove all the hot/warm pixels which will improve the result from your existing data. This page will help with the process:
http://pixinsight.com/forum/index.php?topic=4218.0Mike