pixinsight evaluates the noise in your lights and scales the master dark frame accordingly. this is why the temperature/duration of the dark is not nearly as important as it is in other programs. so there's no need to have an extensive dark library or match up darks of different duration/temperature with your lights. that kind of eliminates the need for a whole binning infrastructure.
There are several camps on calibration frames. One likes to take them each imaging session, another likes to use scaled darks along with their flats, and then there is the camp I'm in where I have plenty of hard drive space and cloudy/moon lit nights that allow me to keep a dark library with a range of temperatures and lengths (although I almost exclusively expose for 20 minutes with exception of 30 minutes for Ha) as well as bin 1 and 2. While this may not be the most economic of time approach, it's for the most part quite easy to setup as a sequence in MaxIm. I do automatic sky flats using ACP so that's painless. What is most important is that the frames used create a well calibrated image. A current matched master dark, made with sufficient sub-frames (usually 20-30 for me either Median or Sigma combined) , does an excellent job. Not sure how any program is going to change that. Flats will either work or not. Making proper flats within the linear range of the camera, usually 25-50% of saturation, is key as well as enough to increase the signal to noise ratio of the master frame. I have a tendency of taking darks every season, 3-4 months apart, and take flats at that same time. Masters are created and named including the date for use should I decide to reprocess an image sometime down the road. I am aware of scaled darks but have yet to have as good a reduced image as I get with non-scaled darks so I quit trying that.
I'm not saying it doesn't work, just not for me. The bottom line is getting the best results for you using whatever method works best for you. Again, I have owned MaxIm for many years and it does this well. I need a program, in this case MaxIm for using ACP, so I might as well use it's strengths. After calibration, it's almost always 100% PI until I make my JPG files for the website. Then I use Photoshop. I already own it and it gives me previews of the images and size before creating them.
Steve