Hi Georg,
Noise is uncertainty in the data. For this reason, the signal-to-noise ratio cannot be evaluated in a single image, unless you have an a priori, perfect knowledge of the signal. Perfect means here with no uncertainty. Such an a priori knowledge would only be possible if you could control the whole image generation process, as in synthetic image renditions for example. Of course, that never happens with real-world images, and very especially it doesn't happen with astronomical images —or noise reduction would consist of a simple subtraction, and deconvolution would always work as an ideal process!
The stochastic nature of the noise allows us to guess a noise estimate, based on statistical properties, assuming a particular probability density function of the noise in the image, or noise distribution. Usually, the Gaussian distribution is used to this purpose; sometimes also the Poisson distribution because it can be used to model photon counting processes. PixInsight computes noise estimates using high-accuracy multiscale, wavelet-based algorithms.
So in real-world images, signal-to-noise measurements are always relative, never absolute. For example, we can estimate how the SNR improves after a given process, by measuring the importance (in statistical terms) of the noise before and after the process. Of course, this only works if we know that either the signal remains constant during the process, or we can predict how the signal changes during the process. PixInsight does this as part of its standard ImageIntegration tool, in order to provide an estimate of the quality of the integration procedure.