This problem has not been reported before, and cannot be reproduced on any of our working and testing machines, on any supported platform. The mouse wheel works perfectly on all machines we have used to test PixInsight 1.8.6.
On Windows, weird problems like these can happen because of defective or outdated graphics drivers. Check that you have the latest versions of your graphics drivers installed. Intel graphics drivers are particularly problematic. Are you running PixInsight on a Surface, or on a similar tablet-like machine?