Thank you for uploading the image and the video. I can reproduce exactly the same problem that you have on Windows 10 with Larry's image. However, the same image works perfectly with DBE on OS X and Linux, and I cannot reproduce this problem with any other image on Windows, irrespective of file formats.
As Mike says, if I save Larry's image in TIFF format, then there is no problem with DBE. I have tried many different modifications to the image, including disabling color management, changing the embedded ICC profile, adding pedestals, cropping, resampling, interpolating the data in different ways, and destroying image properties. No matter what I do, this image always reproduces the same problem.
Frankly, this is one of the weirdest things I've seen in many years. Looks like paranormal
![smile :)](http://pixinsight.com/forum/Smileys/default/smile.gif)
Seriously, I want to get to the bottom of this problem. From my experience, I suspect this is a Visual C++ compiler bug. I'll try to switch to VC++ 2015 ASAP (currently we are using VC++ 2013), which probably will solve the problem "automagically". Anyway, it is clear that this image has something that triggers the bug in some way, and I want to discover it. If you could upload at least another image that causes the same problem, preferably a very different image if possible, that would help me a lot.
While I fix this issue, the workaround is simple: Instead of clicking "Execute" on DBE (green check mark button), drag the New Instance icon (blue triangle). On all my tests at least, DBE works perfectly with this image if applied this way.