Do you know the MosaicByCoordinates script by Andres del Pozo? You have it readily available and fully documented in PixInsight.
MosaicByCoordinates can generate ultra-wide field mosaics very easily with high accuracy, PixInsight's native floating point and XISF support, and a prescribed projection system. The tool you mentioned in your post is a generic panorama making program, which will stitch your frames inaccurately and without any control on the geometry of the generated mosaic, besides forcing you to degrade your data to 16 bits and an inferior file format.
That application can work for daylight panoramas (although there are much better solutions, including free/gratis ones not based on patented algorithms), but it is definitely a bad choice for astronomical images.