Usually this error means that you don't have the required permissions to write update packages. On OS X, you should update PixInsight from an "administrator" user account.
An alternative solution can be:
- From the main menu, select: Edit > Global Preferences
- On the Preferences interface, select the "Directories and Network" item on the left side.
- Under the "Downloads directory" field, click "Select directory..." and change the default "/tmp" to a folder where you have read/write access. For example, a folder that you can create on your home folder.
- Press F6 to apply the tool.
This should fix the problem.