Thanks for all your advices.
Just one point: I only have a series of 32 frames taken at the same position, and two frames only with a different angle to see the difference (also taken the day after). The colors - as I mentioned - cover the whole rainbow space, ie it´s not in one channel only. Therefore, unfortunately I cannot subtract easily the colored noise.
I wanted to upload a picture, but it does not work although I used less than 512 KB in jpg format.
So, I wonder of how to get the stars and the galaxy separated from the background. One way I thought about was using a mask (for each channel) where I deleted all stars and the galaxy?
Of course, amending the tubus architecture would be one way, but now I have the frames...
Many thanks Wolfgang