Let's see...
15,327*14,994*3*8 = 5,517,352,152 bytes = 5.138 GB
Unfortunately, the TIFF format uses 32-bit file offsets internally, and hence is limited to slightly less than 4 GB of pixel data. There is an unofficial BigTIFF format out there but the current TIFF support module implements the TIFF version 6 standard (LibTIFF library).
Why a 64-bit format? Why not 32-bit floating point, which would allow you to stay far away from the 4 GB limit? And why not the FITS format (which does not have these size limitations) instead of TIFF?
Obviously, there is a bug in the fact that PI shouldn't allow you to generate a TIFF file larger than 4 GB. I'll fix this in the next version.
Sorry for the wasted (almost) day. On a side note, to work with such huge mosaics you need a beefy machine. I'd recommend a minimum of 24 or 32 GB of RAM and a latest-generation i7-extreme or Xeon processor.