I installed the latest version yesterday and then installed all the upgrades it recommended - it claims to be version 1.08.00.0963, and I think it has a memory leak in the registration process.
I am building a 3 panel mosaic, with about 1250 images per panel, and I started 3 instances of PI running because the registration processes doesn't seem to be very parallel, and I have enough cores and memory (and not enough patience :-) to run multiple registrations at once.
It was running fine when I went to bed, but this morning, instead of being done they are all almost frozen -- occasionally it shows some activity on the console, but it is very slow, and each of the process has grown to about 12.5GB, and they are each using about 1/2 of 1 CPU core.
I saw this once before, but didn't report it here, so it seems to be reproducible, although it takes a while to make happen.
I've attached a directory listing sorted by date/time. You can see the time between images growing.
Bret