Hi Georg,
you're probably right. The area of different sources of noise in digital imaging is something I always kind of ignored - I should take a look at it to understand it through.
Still I believe that 100x1 = 10x10 only if number of detected photons during 1 minute exposure is high enough - and for faint stuff, we really talk about several photons per minute. But read noise probably plays much bigger role in the result.
My personal experience is to use exposure as long as I can - then I'm able to reveal much fainter stuff in the final picture. Otherwise, what would be the reason to calculate sky-limiting exposure for instance?
Back to original question of Sergio. My suggestion is following: more exposures would definitely help, but I would not forsake length of the exposure to it. You can see that noise is worse in darker areas - where the SNR is low. This is normal. Some amount of noise in uncooled DSLR is inevitable (it's much better in winter BTW). When processing, keep the dark areas dark and use mask to protect them from stretching histogram and increasing saturation. Use inverted mask when applying ACDNR to protect areas with high SNR from damage.
Also, my personal opinion is that it's better to leave some small amount of noise in the image rather than trying to remove it completely. It gives image more realistic and perceptually sharper look. If you are too aggressive with denoising, image can get "washed" or "hand-painted" look. But of course, it strongly depends on quality of original data.
regards, Zbynek