In a couple of weeks, once Juan gets v1.6.0 rolled out, then the WHOLE calibration process will be aceivable 'inside' PixInsight.
I am already using nothing but PI for calibrating my images and, despite the many 'manual' steps involved, the results are well worth the effort, far exceeding the quality of calibration and integration that I have acieved by any other means.
I would therefore say that, eventually, PI will be able to simply take the data acquired by other means, and will provide all the subsequent steps and stages needed to generate a complete image.
Cheers,