I have a greenish 3 pointed "artifact" I think, see circled area in attachment. I'm a Pixinsight novice so I don't know if I've introduced something here. When I review others work with this object I don't see this structure. I imaged the Rosette Nebula earlier in the evening with the same setup as below, CCD untouched. There is no "artifact" in the Rosette.
Taken with a RASA 8, QHY12, 24 x 300 sec subs, PHD2 guiding, Pixinsight Batch Preprocessing and post-processing.