I'm out of my depth here.
I "went back to basics." By that I mean . . .
1/I uninstalled PI v. 1457.
2/ I reinstalled a previous version, v. 1448.
3/ I loaded the BPP with .fits files as they come from the camera, for all frames, lights, darks, flats and bias frames.
4/ I then ran the BPP twice. Once with the "up-bottom FITS" box checked and again with it unchecked.
Same result each time. It was evident, from the break in the column defect, that checking/unchecking the "up-bottom FITS" box DID "vertically mirror" the resulting master dark. New masters were created on each run. Still, the resulting calibrated sub looked the same, i.e. severely clipped.
Attached is a single calibrated Ha frame, with the histogram displaying the stretch from the STF default. Also attached is the same single un-calibrated sub with its histogram from the STF default.
Not sure what to make of Bernd's suggestion? After I double click on Format Explorer/FITS. I attach that panel also. That panel is identical to that on both the machine with the current version of PI and the old machine with an ancient version.