Hi Farzad,
Yes, Mike is basically correct. If you are working on any image where most of the data is 'foreground nebulosity', then there might be very little in the way of 'background' for the DBE Process to work with.
If you can find areas of the image that you know are indeed 'background', just pop a DBE marker into them (avoiding stars, as per normal) - then see what DBE gives you, not just as a final image, but also as the background image PI intends to use to correct the original. Quite often, a thorough investigation of the extracted background can tell you a lot about what you are actually working with,
Hope this helps.