Hi Rob,
Thanks for your input. I sometimes use Frame Adaption, depending on the results. In GMM, I use various setting for file order, overlay and average. The biggest issue is each row of the mosaic was shot on different nights over 3 months. I crop, abe, histo stretch, mlt, mask, tvg, histo, curves. Then on to SA and GMM. Each row of images (same night shooting) mosaics nicely. But, when adding the images from next row, the backgrounds are too different.
I will try your suggestion with DNALinearFit. Thanks again!
John