Hi,
I some time get "..Invalid memory read.." on different functions, in this case TGVDenoise when clicking "Local support check box". Made NR on a loaded FITS 16 image.
PixInsight Standard Edition
Version 01.08.04.1195 Ripley (x64)
Running on Windows 10 64bit
Solution is often to restart PI (also worked this time). I think you have some kind of memory cash problem, PI was started some days before the problem.
Best regards,
/Christer