Hi Greg,
Unfortunately there is no single solution that will apply to every user, and not even a fixed solution that could be proposed for PI users in general (my own method has been carefully thought out, yet it still changes!!) Also, any method you choose to base your plans on has to be one that is compatible with your particular imager (or selection of imagers - one that suits an OSC my not suit a DSLR, and would certainly not be suitable for mono imagers).
So don't waste time and effort hunting the Web for your 'pot of gold at the end of your rainbow' Let us know what your detailed equipment setup is, and the types of objects you might be thinking of imaging, and someone may be prepared to guide you through the way 'they' do things.
One nugget of information that has worked for me is to buy plenty of HDD storage and to perform regular backups (I do this every hour), and I backup to several different physical devices, at several different physical locations, and I am always on the lookout for any storage bargains that are worth the money - but limit all my drives, RAIDed or otherwise, to 2TB because even that is a lot of storage to have to restore if the worst happens . . .