The error message describes the problem: a required swap file either does not exist, or it cannot be accessed for any reason. A PixInsight project uses swap files to store image states. Swap files, along with the process instances that originate them, are the most critical elements of a project.
Swap files should never be removed or damaged while a running instance of PixInsight depends on them. However, errors happen. It's difficult to say more without knowing what happened when you were working with your data. This could be a system error, a software conflict (typical invasive behavior of some virus protection software on Windows), a hardware error, and of course a PixInsight bug. In the latter case, we need a repeatable pattern in order to understand and eventually fix any nontrivial issue.