Hello Jack and Carlos,
This is a really odd problem. I have been unable to reproduce it on any of my machines running XP SP1 and SP2, and Win2K SP4. However I don't have a dual core processor, although I don't think this can make a significant difference.
I have a question for Jack: are you using a wireless keyboard and/or mouse in your computer? If yes, then this could be the origin of the problem. It is amazing how many and how odd problems a wireless device is able to generate. If this is the case, could you try PI with a wired mouse and keyboard to see if the problem disappears?
Thank you very much for your support.