Hi. You can also do this from PixInsight. On UNIX and Linux versions of PI, enter this command from the command line (at the bottom of the Process Console window):
!!$PXI_BINDIR/PixInsight
The two leading bangs (!!) run an external program, the PixInsight executable in this case, as an independent process. This is known as a daemon on Linux/UNIX. If you use a single bang, the newly created process runs as a child of the current PI process, which blocks it.
On Windows, this is a bit more complicated (Windows doesn't love command lines):
cd "$PXI_BINDIR"
!!cmd.exe /C PixInsight.exe