This is an icon problem different from what others have reported.
I have PixInsight pinned to the taskbar in Windows 10. (Right-click on the tile in the Start Menu, choose More..., Pin to Taskbar.)
Since I upgraded to the latest version a couple of months ago, this icon became a white rectangle rather than the PixInsight diamond.
What I think is wrong is that one particular size of icon -- the one needed for display on the taskbar -- is missing or incorrect in PixInsight.exe. [Probably not the case; see below.]
It may even have already been fixed -- I don't know. It's something PixInsight updates would not be expected touch. I'm going to re-download the whole installer and reinstall PixInsight.